The Skin Barrier in Patients with Lichen Simplex Chronicus
نویسندگان
چکیده
منابع مشابه
Lichen simplex chronicus with a cutaneous horn.
A 55-year-old male developed itching on the anterior aspects of both legs and the right ankle. Gradually over the next 5 years there was thickening of the skin on these areas followed by the appearance of hyperpigmented, scaly, severely itchy plaques. He also noticed the appearance of a thick, hard horn-like structure projecting from the surface of the right ankle lesion for the last 2 years. A...
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Emotional tensions in predisposed subjects may play a key role in inducing a pruritic sensation, leading to a scratching that, becoming a self-perpetuating pathomechanism, may represent the main feature of two distinct cutaneous clinical entities: prurigo nodularis and lichen simplex chronicus. Psychogenic factors play a relevant role in both conditions, and they are often associated with depre...
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A 49-year-old woman presented to the dermatology department with a 10-year history of anogenital itching. The pruritus was often so severe that she would scratch until she drew blood. Her symptoms had been partially controlled with Dermovate NN cream during the year prior to her presentation but were still impacting heavily on her quality of life. She denied the use of wet wipes, soap or pant l...
متن کاملLichen Simplex Chronicus That Accompanies Anogenital Warts during the Childhood
Anogenital warts and lichen simplex chronicus (LSC) are rarely seen during the childhood. A 9-year-old girl has been presented to hospital by her parents with itching in the anogenital area. There were anogenital warts and a different erythematous lesion in the perianal region. On the pulpa of the right thumb, there was a wart extending under the nail. The lesions are surgically removed. The re...
متن کاملAlterations in the LINE-1 methylation pattern in patients with lichen simplex chronicus.
BACKGROUND Long interspersed element-1 (LINE-1) and short interspersed element (Alu) retrotransposons have been identified to influence the human genome by modifications in gene expression. Variations in LINE-1 and Alu methylation have been shown to be associated with many diseases, predominantly malignancies and autoimmune diseases. Moreover, the degree and pattern of LINE-1 methylation are re...
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ژورنال
عنوان ژورنال: Journal of Clinical Research in Dermatology
سال: 2016
ISSN: 2378-1726
DOI: 10.15226/2378-1726/3/3/00131